159
4
1
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T60075 | Dopamine D2 receptor agonist-2 | Dopamine D2 Receptor | Dopamine Receptor |
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor. | |||
T11077 | Dopamine D2 receptor antagonist-1 | Others | |
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity. | |||
T7635 | Raclopride | Dopamine Receptor | |
Raclopride is a selective antagonist of dopamine D2/D3 receptor. | |||
T4007 | Eticlopride hydrochloride | Dopamine Receptor | |
Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM). | |||
TQ0084 | Lumateperone Tosylate | ITI-007 | Dopamine Receptor , 5-HT Receptor |
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM). | |||
T16392 | ONC206 | Dopamine Receptor | |
ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and possesses broad-spectrum anti-tumor activity. | |||
T0280 | Spiperone | Spiroperidol,Spiropitan | Dopamine Receptor |
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA. | |||
T21069 | Lumateperone | ITI 722,ITI722,ITI-007,ITI007 | 5-HT Receptor |
Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM). | |||
T7943 | Fluphenazine decanoate | Dopamine Receptor | |
Fluphenazine decanoate is dopamine D2 receptor blocke,and is a long-acting phenothiazine neuroleptic that used to treat schizophrenia. | |||
T8136 | Perospirone hydrochloride | Perospirone HCl,SM-9018 hydrochloride | Dopamine Receptor , 5-HT Receptor |
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. | |||
T2226 | Pergolide mesylate | Pergolide mesylate salt,LY127809,Pergolide methanesulfonate | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Pergolide mesylate salt(LY127809) is a long-acting dopamine agonist which has been used to treat PARKINSON DISEASE and HYPERPROLACTINEMIA but withdrawn from some markets due to potential for HEART VALVE DISEASES. | |||
T10683 | Carmoxirole hydrochloride | EMD 45609 hydrochloride | Dopamine Receptor |
Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo. | |||
T9228 | Propionylpromazine hydrochloride | Propiopromazine hydrochloride | Dopamine Receptor |
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist. | |||
T70302 | Fallypride | Dopamine Receptor | |
Fallypride is a potent and selective dopamine D2/D3 receptor antagonist. | |||
T6142 | PD128907 HCl | Dopamine Receptor | |
PD128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor. | |||
T22817 | GSK 789472 hydrochloride | GSK-789472 HCl,1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride,4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one | Dopamine Receptor |
GSK 789472 hydrochloride is both a dopamine D3 receptor antagonist and a D2 partial agonist. | |||
T0302 | Triflupromazine hydrochloride | Neoprin,Fluopromazine hydrochloride,Fluorofen,Flumazin | Dopamine Receptor , 5-HT Receptor , AChR , Autophagy |
Triflupromazine hydrochloride (Fluopromazine hydrochloride), an antipsychotic medication, is Dopamine D1/D2 receptor antagonists. | |||
T12606 | Quinpirole Hydrochloride | LY 171555,(-)-LY 171555 | Dopamine Receptor |
Quinpirole Hydrochloride (LY 171555), as an agonist with high affinity for dopamine receptor D2/D3, has been widely used to study the function of dopamine receptor D2/D3 in humans and mice | |||
T7180 | Sultopride hydrochloride | LIN-1418 hydrochloride | Dopamine Receptor |
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective dopamine D2 and D3 receptor antagonist. | |||
T24613 | PF-00217830 | PF-217830 | Dopamine Receptor , Serotonin Transporter |
PF-00217830 is a serotonin 1A receptor agonist, dopamine D2 receptor agonist, and serotonin 2A receptor antagonist.PF-00217830 may be used in the study of schizophrenia. | |||
T3187 | Fluoroclebopride | Dopamine Receptor | |
Fluoroclebopride is a dopamine (DA) D2 receptor ligand. | |||
T2564 | Cis-(Z)-Flupentixol dihydrochloride | Emergil,Flupenthixol dihydrochloride | Dopamine Receptor , 5-HT Receptor |
cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist. | |||
T14083 | Abaperidone | Dopamine Receptor , 5-HT Receptor | |
Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound th... | |||
T38754 | Trazpiroben | TAK-906 | Dopamine Receptor |
Trazpiroben (TAK-906) is a selective dopamine D2/D3 receptor antagonist used in the study of gastroparesis. | |||
T27677 | JNJ-37822681 | JNJ37822681,JNJ 37822681 | Dopamine Receptor |
JNJ-37822681 is a novel, highly selective dopamine D₂ receptor antagonist characterized by a rapid dissociation rate from the dopamine D₂ receptor. | |||
T3431 | Pardoprunox hydrochloride | SLV-308 hydrochloride,DU-126891 hydrochloride | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept... | |||
T0990 | Droperidol | NSC 169874,Dehydrobenzperidol | Dopamine Receptor |
Droperidol (Dehydrobenzperidol) is a Dopamine-2 Receptor Antagonist. The mechanism of action of droperidol is as a Dopamine D2 Antagonist. | |||
T14767 | BP 897 hydrochloride | Dopamine Receptor | |
BP 897 is a potent and selective agonist of dopamine D3 receptor and it is a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 and D2 receptors. Which shows low affinities at D1 and D4 receptors ... | |||
T21782 | A 77636 hydrochloride | A77636 hydrochloride | Dopamine Receptor |
A 77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A 77636 hydrochloride shows antiparkinsonian activity. A 77636 hydrochloride is functionall... | |||
T1201 | Sulpiride | Aiglonyl,Dogmatil,Sulpyrid,Dolmatil,Dobren | Dopamine Receptor |
Sulpiride (Aiglonyl) is a dopamine D2-receptor antagonist, used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. | |||
T30098 | Aplindore Fumarate | Aplindore,DAB-452 Fumarate,DAB-452 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H... | |||
T28809 | SLV-310 | SLV 310,SLV310 | Dopamine Receptor , 5-HT Receptor |
SLV-310 is a potent dopamine D2 receptor antagonist and 5-HT reuptake receptor inhibitor used in the study of neurological disorders such as bipolar disorder and schizophrenia. | |||
T1069 | Metoclopramide hydrochloride | Maxolon,Metoclopramide HCl | Dopamine Receptor , 5-HT Receptor , AChR |
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. | |||
T5842 | Bromocriptine mesylate | CB-154 | Dopamine Receptor , Autophagy |
Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM) | |||
T12861 | SB-277011 | SB-277011A | Dopamine Receptor |
SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively. | |||
T10232 | Acetophenazine dimaleate | Dopamine Receptor | |
Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression. Acetophenazine dimaleate primarily targets the dopamine D2 receptor. | |||
T9100 | BP 897 | 2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]- | Dopamine Receptor |
BP 897 (2-Naphthalenecarboxamide, N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-) is a potent and selective dopamine D3 receptor agonist, and a weak dopamine D2 receptor antagonist, with Kis of 0.92 nM and 61 nM for D3 ... | |||
T28073 | MLS1547 | MLS000051547,MLS 1547,MLS-1547 | Dopamine Receptor |
MLS1547 (MLS000051547) is a highly efficacious agonist of G protein-biased dopamine D2 receptor with a Ki of 1.2 μM. MLS1547 stimulates D2R G protein-mediated signaling with EC50 of 0.37 μM in a calcium mobilization assa... | |||
T7352 | Pridopidine | ACR16,ASP2314,FR310826 | Dopamine Receptor |
Pridopidine (FR310826), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model. | |||
T7553 | (+)-PD 128907 hydrochloride | Dopamine Receptor | |
(+)-PD 128907 hydrochloride is an agonist of D3 dopamine receptor . | |||
T16472 | Pericyazine | Propericiazine,RP 8909 | Dopamine Receptor |
Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist. Pericyazine is a first-generation antipsychotic drug that is used as an adjunct to the short-term management of severe anxiety states and psych... | |||
T8389 | Trifluoperazine | trifluoroperazine | CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy |
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia. | |||
T13164 | Tipepidine hydrochloride | Potassium Channel , Dopamine Receptor | |
Tipepidine hydrochloride is a reversible inhibitor of dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) (IC50: 7.0 μM), with antidepressant-like effect. | |||
T21337 | Lurasidone | SM-13496 | Dopamine Receptor , 5-HT Receptor |
Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6.75 nM). | |||
T26375 | (S)-Amisulpride | Esamisulpride,(S) Amisulpride,SEP-4199 | Dopamine Receptor , 5-HT Receptor |
(S)-Amisulpride ((S) Amisulpride) (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride is an antagonist at the 5-HT7 receptor with a Ki of 900 nM. (S)-Amisulpride has antipsychotic and antidepr... | |||
T14490 | Talipexole dihydrochloride | Domnin,B-HT 920 dihydrochloride | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Talipexole dihydrochloride (Domnin) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist, and 5-HT3 receptor antagonist in both rat cortical and intestinal membrane fractions with Ki values of 0.35 μM and 0.22 μM, ... | |||
T26360 | Benperidol | R4584,R-4584,Anquil,McN-JR-4584,R 4584 | |
Benperidol (Anquil) is a butanone analog with antipsychotic and stabilizing properties, and has been shown to be effective in blocking D2 receptors.Benperidol can be used in positron emission tomography (PET) scanning to... | |||
T33816 | Ordopidine | ACR-325,ACR 325,ACR325 | Dopamine Receptor |
Ordopidine (ACR325) is a dopaminergic stabilizer that suppresses psychostimulant-induced hyperactivity disorder and stimulates behavior during inactivity. Ordopidine acts as a dopamine D2 receptor antagonist in vitro and... | |||
T13510 | Sigma-LIGAND-1 | Sigma receptor | |
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor. | |||
T11722 | JNJ-37822681 dihydrochloride | Dopamine Receptor | |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1045 | Trimipramine maleate | Surmontil maleate | Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor |
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal... | |||
T15686 | L-741626 | 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole | Dopamine Receptor |
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively). | |||
T14853 | Cabergoline | FCE-21336 | Dopamine Receptor , 5-HT Receptor , Autophagy |
Cabergoline (FCE-21336) is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal a... | |||
T6648 | Rotundine | Gindarine,L-Tetrahydropalmatine,Caseanine,(-)-Tetrahydropalmatine | Dopamine Receptor , 5-HT Receptor |
Rotundine (Gindarine) (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-01201 | DRD2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5. |